AnAttemptWasMade, if Panther Lake is, say, all-in-all, 30% more power efficient, then, sure, it'd be 30%. It'd be 30% less out of not a lot in the first place, you decide if it's worth it. But what you want is a lot of RAM to be able to fit the good/smart LLMs, you also want not the worst GPU performance and Strix Halo (256-bit) is basically 2x vs Panther Lake (128-bit) and I personally wouldn't care less if PL is 30% more power efficient, if I would have to choose between Strix Halo 128 GB RAM vs Panther Lake 64 GB RAM.
Indeed, the next thing may be linking them together, but I don't know how hassle-free it is. Generally speaking, I personally like the idea, but now for small things like NUCs and in this case I would prefer one system. But if linking 4 Panther Lake NUCs (4 * 64 GB RAM) is easy, the perf scales decently well and using it is transparent / hassle-free and equally cheap vs 1 Strix Halo mini-PC, then one could consider it. But it's not going to be equally in price vs just 1 Strix Halo system, so..you decide. The lowest common denominator here is the size, if you _must_ have NUC-sized system(s), then sure, but if not, I'd build a desktop PC (AM5 B850 mainstream mobo supports 4 * 64 GB RAM (and a 4090 for much faster prompt processing)). (and when can one really fit a 4 NUCs or 2 Strix Halo mini-PCs into the room, but can't fit a mid sized ATX desktop PC)
So, I personally would avoid linking Panther Lake NUCs, Strix Halo mini-PCs or any such systems. If anything, I'd ask myself how to link fully loaded 4*64GB RAM B850 mobo desktop PCs together and if it makes sense in the first place / is it hassle-free in the usage or should I instead go bigger and get a server mobo. I think, I would again avoid linking and go with a (used) server mobo. Granted, at some point, one has to link servers together (because 1 server mobo is as big as it gets in one system).
If you really want to link, inform yourself if it's worth it first. A desktop PC is not going to be less power efficient and in prompt processing all systems will be equally power efficient, Panther Lake might be a full node more power efficient (~30%), but ask yourself if the total Wh consumed are going to be worth all the hassle and the higher price, as Panther Lake is a new thingy, and new things come often with an unreasonable price to performance.