Microsoft has become much more open under current CEO Satya Nadella with apps made for macOS, iOS, Android and Linux. The latest step in this initiative is the porting of a version of Microsoft Defender antivirus software for macOS, but in this instance, it is targeted at business users initially.
https://www.notebookcheck.net/Microsoft-Defender-to-launch-on-the-Mac.414851.0.html
I got this only protection for years and no virus. But the best protection is between your chair and the keyboard... ;)