AMD's upcoming Instinct MI300 HPC accelerator may turn out to be an APU instead of just a GPU. The MI300 is now being rumored to integrate a Zen 4 CPU, a CDNA 3-based GPU, and shared HBM memory to create what could be the world's biggest x86 exascale APU for datacenters.
https://www.notebookcheck.net/AMD-Instinct-MI300-to-be-world-s-biggest-x86-exascale-APU-with-integrated-Zen-4-CPU-CDNA-3-GPU-and-shared-HBM-DRAM.619755.0.html