Well for a start AMD drivers are miles ahead of intel, especially on Linux where a gaming and handheld oriented distro like bazzite doesn't work well at all on intel.
MSI now also offers its gaming handheld Claw 8 with an AMD processor. The question is why though, because our review reveals some ergonomic drawbacks compared to the Intel SKU and you also get 8 GB RAM less. The price is identical, so why should you get the AMD version?