I don't really see that as significant. History has shown, that people within the AI/LLM field are willing to pay near limitless amounts of cash to get what they want.
So, based on that, why is 256-bit bus significant when there is hardware out there with 512-bit bus?
Sapphire has showcased a brand-new gaming mini PC, powered by up to an AMD Ryzen AI Max+ 395 "Strix Halo" APU with 16-cores and a powerful Radeon 8060S GPU that trades blows with desktop-class discrete GPUs. Pricing and availability details for the mini PC are under wraps for now.