Contrary to some Korean sources that were previously claiming the S-Pen support would not be added to the Fold 2, the latest leaks point out that Samsung's S-Pens will indeed work with the upcoming foldable. Additionally, the inner screen is getting an upgraded 120 Hz panel and both outer and inner displays now feature punch-hole cameras.
https://www.notebookcheck.net/Latest-Galaxy-Fold-2-leaks-outer-and-inner-display-detailed-specs-S-Pen-support-in-the-books-after-all.462141.0.html
If they could guarantee that the S-Pen doesn't wear down the...whatever's on the surface of the inner screen, nor puncture or crack the rigid layers of the screen with pressure consistent with writing, then they've certainly got a unique product on their hands.