Certainly, throttling will be an issue to users wanting to edit audio, video or 3D drawings.
Anybody who plans to play an occasional game will also suffer.
Pure office users may not run into throttling, but for them, there's still a major issue with Microsoft's product: Its glued together and can't be upgraded or repaired by yourself or the shop at the corner.
Not to mention that Microsoft thinks your computer is really theirs and you just get to use it in the way they deem fit, as demonstrated by Microsoft's admission, that Windows updates can and will remove software from your system unasked, without prompt. We're not talking pirated stuff here either, we're talking anything the logic of the present windows update doesn't like...
After its finished, you want to continue your work, but your software, its gone! This has included Office Pro 2016, Capture One Pro, for example.
Please send Microsoft the bill for missed deadlines :)